Adult Weight Gain Increases Risk of Prostate Cancer


	Adult Weight Gain Increases Risk of Prostate Cancer Led by Margaret E. Wright, Ph.D., of the Division of Cancer Epidemiology and Genetics at the National Cancer Institute in Bethesda, MD, researchers followed 287,760 men, ages 50-71 years as part of the NIH-AARP Diet and Health Study to examine the individual impact of BMI and adult weight change on the incidence, severity and outcome of prostate cancer. The researchers found that higher BMI and weight gain since the age of 18 were associated with significantly higher risk of death from prostate cancer. As BMI increased, so did the relative risk of death from prostate cancer. Men who were overweight (BMI 25-29.9) had a 25 percent higher risk, mildly obese men (BMI 30-34.9) had a 46 percent higher risk, and severely obese men (BMI greater than 35) had a 100 percent, or doubled risk. Similarly, men who gained weight since the age of 18 were also at increased risk of a fatal outcome. Neither overweight nor obesity, however, was associated with developing prostate cancer. That obesity did not impact the incidence of prostate cancer is consistent with findings from most other studies. However, that "BMI and adult weight gain were each linked with higher prostate cancer mortality," significantly links "adiposity to prostate cancer progression leading to death," conclude the authors. This study is significant because both the rate of increase in obesity and the absolute numbers of obese adults have increased over time. In the U.S., for example, the number of states reporting obesity rates greater than 20 percent increased from zero in 1985 to 46 in 2005. Today, 30 percent of American adults are categorized as obese -- i.e., a BMI greater than 30. Obesity has been linked to a host of chronic medical problems. Article: "Prospective Study of Adiposity and Weight Change in Relation to Prostate Cancer Incidence and Mortality," Margaret E. Wright, Shih-Chen Chang, Arthur Schatzkin, Demetrius Albanes, Victor Kipnis, Traci Mouw, Paul Hurwitz, Albert Hollenbeck, Michael F. Leitzmann, CANCER; Published Online: January 15, 2007 (DOI: 10.1002/cncr.22443); Print Issue Date: February 15, 2007. Note: This article has been adapted from a news release issued by John Wiley & Sons, Inc.	PROSTATE PROBLEMS (home) PSA Test PSA Test PSA Test PSA Test PSA Test PSA Test PSA Test PSA Test PSA Test PSA Test PSA Test Increased Weight, BMI Raise Prostate Cancer Risk.: An article from: Family Pr... by Mitchel L. Zoler Amazon Price: $5.95 Data mixed on obesity's effects on prostate ca.(Urology): An article from: In... by Sherry Boschert Amazon Price: $5.95 Data are mixed on impact of obesity on prostate cancer.(Across Specialties): ... by Sherry Boschert Amazon Price: $5.95
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